323 research outputs found

    Colonoscopy: Advanced and Emerging Techniques-A Review of Colonoscopic Approaches to Colorectal Conditions.

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    A complete colonoscopy is key in the diagnostic and therapeutic approaches to a variety of colorectal diseases. Major challenges are incomplete polyp removal and missed polyps, particularly in the setting of a difficult colonoscopy. There are a variety of both well-established and newer techniques that have been developed to optimize polyp detection, perform complete polypectomy, and endoscopically treat various complications and conditions such as strictures and perforations. The objective of this article is to familiarize the colorectal surgeon with techniques utilized by advanced endoscopists

    Nickel-substituted Lithium-Zinc-Manganese Ferritefor the Suppression of Radiated Emission Noise

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    Nickel-substituted lithium-zinc-manganese ferrite of the composition,  Li0.25-x/4 Zn0.5-x/2NixMn 0.1Fe2.15-x/4O4 where x = 0, 0.1, 0.2, 0.3, 0.4, 0.5 have been investigated for electromagnetic interference(EMI)  suppression to meet the EMI standards. Various compositions were prepared by theconventional ceramic technique using mixed oxides. The ferrites were characterised for theirstructural, electrical, and magnetic, properties. The ferrites were found to posses high saturationmagnetisation, permeability, Curie temperature and resistivity, which are the desirablecharacteristics for noise-suppression application. The operating frequency of the ferrite rangedfrom 1 MHz–700 MHz, which is high enough for absorbing the electrical fast transients andradiated emission noise suppression as shown for three devices–currency counting machine,energy meter and dc-dc converter where the radiated emission noise  is suppressed from 10 dBto 20 dB. In energy meter where the electrical fast transients (EFTs) are suppressed up to 5.5kV, 4.5 kV, 3.5 kV, 2.8 kV, 1.6 kV, and 1.2 kV with composition x = 0, 0.1, 0.2, 0.3, 0.4, 0.5, respectively.This material has tremendous scope of application in military equipment  to comply the EMIrequirements of the military standards

    Incarcerated foreign body in the vagina of a postmenopausal lady

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    Vaginal foreign bodies retained for long duration are uncommon in present day scenario. When a female presents with recurrent foul smelling vaginal discharge, foreign body should be suspected. Here is a report of foreign body in the vagina of a postmenopausal lady

    FACILE SYNTHESIS, SPECTRAL STUDIES, DFT CALCULATIONS AND BIOLOGICAL ACTIVITIES OF NOVEL NI (II), CU (II), AND PD (II) COMPLEXES OF THIADIAZOLE ANALOGS

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    Objective: A facile synthesis of some novel Schiff base derivatives of 2-substituted-5-amino-thiadiazoles along with their Ni (II), Cu (II), and Pd (II) complexes were achieved by sonication and the conventional method. In addition to establish the structure by DFT studies and to explore antimicrobial and anticancer activities of these novel compounds.Methods: The precursor 2-substituted-5-amino-thiadiazoles (T1-T3), target ligands and their metal complexes were synthesized by ultra-sonication and conventional means. The isolated products were thoroughly characterized by physical and spectroscopic techniques including 1H-NMR, [13]C-NMR and IR spectroscopy. All characterized compounds were screened for antimicrobial activities using well diffusion method, and MTT assay was performed for cytotoxicity.Results: All novel compounds were synthesized by a green route i.e. ultra sonication and a noticeable improvement in yield with shorter reaction time than the conventional method were observed. The octahedral geometry was proposed for Ni (II)/Cu (II) complexes whereas square planar for Pd (II) complexes on the basis of the spectral techniques which were supported by DFT analysis by Gaussian03. On the analysis of antimicrobial activities, the compound T7 and T10 showed maximum antibacterial and antifungal activities respectively. However, compounds T25, T37, T31 found to be a potential cytotoxic compound with IC50 value 0.469, 0.865 and 1.131 μM respectively.Conclusion: Analysis of synthetic protocol, it could be concluded that ultra-sonication is the better method to synthesize these potential biological active moiety. On the whole Cu (II) and Ni (II) complexes showed promising activity towards all microorganisms while Pd (II) complex emerged an excellent moiety in carcinoma cell line

    Electron-Hole Asymmetry in the Electron-phonon Coupling in Top-gated Phosphorene Transistor

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    Using in-situ Raman scattering from phosphorene channel in an electrochemically top-gated field effect transistor, we show that its phonons with Ag_g symmetry depend much more strongly on concentration of electrons than that of holes, while the phonons with Bg_g symmetry are insensitive to doping. With first-principles theoretical analysis, we show that the observed electon-hole asymmetry arises from the radically different constitution of its conduction and valence bands involving π\pi and σ\sigma bonding states respectively, whose symmetry permits coupling with only the phonons that preserve the lattice symmetry. Thus, Raman spectroscopy is a non-invasive tool for measuring electron concentration in phosphorene-based nanoelectronic devices

    POTASSIUM FERTILIZATION FOR DIRECT SEEDED BASMATI RICE

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    Not AvailableThe effect of potassium (K) application based on 4R stewardship (right rate, time, method, and source) on growth, yield attributes and yields of dry direct seeded basmati rice (Oryza sativa L.) was evaluated during rainy (kharif) season of 2015 and 2016 at IARI, New Delhi. Application of recommended dose of K (60 kg/ha), half as basal and remaining half at panicle initiation (PI) stage increased the grain (5.4 t/ha) and straw yields (7.65 t/ha) by 10 and 4% respectively, over applying the full dose as basal. A strong, positive and significant correlation was observed between yield attributes [panicle weight (r2=0.79), panicle length (r2=0.83), fertility % (r2=0.84)] and yield of dry direct seeded basmati rice. Similarly, positive and significant correlation was observed between leaf area index at 60 DAS (r2=0.73) & 90 DAS (r2=0.91) and dry matter production. The two foliar sprays of 2.5% potassium nitrate (1st at active tillering, and 2nd at panicle initiation) increased fertility (83.5%) and grain yield (4.3 t/ha) by 6% and 8% respectively, over control. However, the combined application of foliar sprays and two split application of recommended dose of K showed non-significant effect on growth, yield and yield attributes. Thus, to obtain higher yield in dry direct seeded basmati rice, application of 60 kg/ha, half as basal and remaining half at panicle initiation (PI) is recommended.Not Availabl

    Physico-chemical Characterization of Biochar from Selected Ligno-cellulosic Biomass for The Sustainable Utilization

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    Biochar is a thermal decomposition product known to mitigate climate change and a supplement to enhance soil fertility. The fine-grained, highly porous structure of biochar makes it a popular choice in environmental research. This study aims to assess the Physico-chemical properties and morphological changes in the biochar prepared from feedstocks: sawdust, sugarcane bagasse, and soapnut pith of Sapindus trifoliatus, native to the foothills of Western Ghats, Kerala, at a temperature of 300 oC and 600oC with 30 minutes residence time. The pyrolytic temperature and feedstock type may affect the yield, ash content, volatile matter (VM), fixed carbon (FC), and nutrient composition of biochar. The selection of these two factors is critical before proceeding with charring. The efficiency of biochar was determined through proximate, ultimate, and morphological characterizations. The pH of high-temperature biochar (sawdust biochar, sugarcane bagasse biochar, and soapnut pith biochar prepared at 600oC) was more alkaline (≥7) compared with low-temperature ones. The char yield was highest at 300oC, whereas the fixed carbon was limited. The VM/FC ratio of SDB600 at 1.09±2.3 represents the highest aromaticity and long-term stability. Therefore, SDB600 can be recommended for soil supplementation purposes. The macrospores were uniformly distributed throughout the biochar surface. Sugarcane bagasse pyrolyzed at 600oC (SBB600) possessed the minimum pore diameter (0.87-9.17µm), with the highest surface area; so that it could be an optimum habitat for soil microbiota as well as a suitable adsorbent for environmental remediation applications. The study suggests that biochar made from these ligno-cellulosic feedstocks is a sustainable tool and a value-added product for environmental management

    Open Access Extracts from Acacia catechu suppress HIV-1 replication by inhibiting the activities of the viral

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    Background: Acacia catechu (Mimosa family) stem bark extracts have been used traditionally as a dietary supplement as well as a folk medicine given its reported anti-inflammatory, immunomodulatory, hepatoprotective, antioxidant, anti-microbial and anti-tumor activities. The present study was undertaken to evaluate the anti-HIV-1 activity of the extracts from stem bark of A. catechu. Methods: The aqueous and 50 % ethanolic extracts of A. catechu stem bark were prepared and 50 % ethanolic extract was further fractioned by successively partitioning with petroleum ether, chloroform and n-butanol. All the extracts and fractions were evaluated for cytotoxicity and anti-HIV-1 activity using different in vitro assays. The active n-butanol fraction was evaluated for its inhibition against HIV-1 reverse transcriptase, integrase, protease, pro-viral genome integration and viral Tat protein mediated transactivation. The effect of n-butanol fraction on the induction of pro-inflammatory cytokines secretion in Vk2/E6E7 cells and transepithelial resistance in Caco-2 and HEC-1A cells was investigated. Results: The aqueous and 50 % ethanolic extracts of A. catechu showed IC50 values of 1.8 ± 0.18 μg/ml and 3.6 ± 0.31 μg/ml, respectively in cell-free virus based assay using TZM-bl cells and HIV-1NL4.3 (X-4 tropic). In the above assay, n-butanol fraction exhibited anti-HIV-1 activity with an IC50 of 1.7 ± 0.12 μg/ml. The n-butanol fractio
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